Resistance to Pentamidine in Leishmania mexicana Involves Exclusion of the Drug from the Mitochondrion
The uptake of [(3)H]pentamidine into wild-type and drug-resistant strains of Leishmania mexicana was compared. Uptake was carrier mediated. Pentamidine-resistant parasites showed cross-resistance to other toxic diamidine derivatives. A substantial decrease in accumulation of the drug accompanied the...
Sábháilte in:
| Foilsithe in: | Antimicrob Agents Chemother |
|---|---|
| Príomhchruthaitheoirí: | , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe / Cruthaithe: |
American Society for Microbiology (ASM)
2002
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| Ábhair: | |
| Rochtain ar líne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC132791/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12435669/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.12.3731-3738.2002 |
| Clibeanna: |
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
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