Heterologous Expression of Trypanosoma cruzi trans-Sialidase in Leishmania major Enhances Virulence

Earlier studies showed that mice primed for a few hours with the trans-sialidase (TS) of Trypanosoma cruzi, the agent of Chagas' disease, become highly susceptible to trypanosomal infection. These studies suggest that TS affects parasite virulence independent of antigenic stimulation. Potential...

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Main Authors: Belen Carrillo, M., Gao, Wenda, Herrera, Macario, Alroy, Joseph, Moore, Jeffrey B., Beverley, Stephen M., Pereira, Miercio A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2000
Assuntos:
Fungal and Parasitic Infections
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC97481/
https://ncbi.nlm.nih.gov/pubmed/10768966
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