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Heterologous Expression of Trypanosoma cruzi trans-Sialidase in Leishmania major Enhances Virulence

Earlier studies showed that mice primed for a few hours with the trans-sialidase (TS) of Trypanosoma cruzi, the agent of Chagas' disease, become highly susceptible to trypanosomal infection. These studies suggest that TS affects parasite virulence independent of antigenic stimulation. Potentially, T...

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Publicado no:Infect Immun
Principais autores: Belen Carrillo, M., Gao, Wenda, Herrera, Macario, Alroy, Joseph, Moore, Jeffrey B., Beverley, Stephen M., Pereira, Miercio A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2000
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97481/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10768966/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.5.2728-2734.2000
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