Resistance to Pentamidine in Leishmania mexicana Involves Exclusion of the Drug from the Mitochondrion
The uptake of [(3)H]pentamidine into wild-type and drug-resistant strains of Leishmania mexicana was compared. Uptake was carrier mediated. Pentamidine-resistant parasites showed cross-resistance to other toxic diamidine derivatives. A substantial decrease in accumulation of the drug accompanied the...
Zapisane w:
| Wydane w: | Antimicrob Agents Chemother |
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| Główni autorzy: | , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Microbiology (ASM)
2002
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC132791/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12435669/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.12.3731-3738.2002 |
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