Structure-Activity Relationship of a New Class of Anti-Hepatitis B Virus Agents

N-Nonyl-deoxy-galactonojirimycin (N-nonyl-DGJ) has been shown to reduce the amount of hepatitis B virus (HBV) produced by tissue cultures under conditions where cell viability is not affected. We show here that the compound N-nonyl-DGJ was effective against lamivudine-resistant HBV mutants bearing t...

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Detalhes bibliográficos
Main Authors: Mehta, Anand, Conyers, Bertha, Tyrrell, D. L. J., Walters, Kathie-Anne, Tipples, Graham A., Dwek, Raymond A., Block, Timothy M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC132742/
https://ncbi.nlm.nih.gov/pubmed/12435712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.12.4004-4008.2002
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