Structure-Activity Relationship of a New Class of Anti-Hepatitis B Virus Agents

N-Nonyl-deoxy-galactonojirimycin (N-nonyl-DGJ) has been shown to reduce the amount of hepatitis B virus (HBV) produced by tissue cultures under conditions where cell viability is not affected. We show here that the compound N-nonyl-DGJ was effective against lamivudine-resistant HBV mutants bearing t...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Mehta, Anand, Conyers, Bertha, Tyrrell, D. L. J., Walters, Kathie-Anne, Tipples, Graham A., Dwek, Raymond A., Block, Timothy M.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2002
Sujets:	Antiviral Agents
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC132742/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12435712/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.12.4004-4008.2002
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