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RAL GTPases are linchpin modulators of human tumour-cell proliferation and survival

The monomeric RAL (RAS-like) GTPases have been indirectly implicated in mitogenic regulation and cell transformation. Here, we show that RALA and RALB collaborate to maintain tumorigenicity through regulation of both proliferation and survival. Remarkably, this task is divided between these highly h...

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Detalhes bibliográficos
Main Authors: Chien, Yuchen, White, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1326339/
https://ncbi.nlm.nih.gov/pubmed/12856001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.embor899
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