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RalGPS2 Is Essential for Survival and Cell Cycle Progression of Lung Cancer Cells Independently of Its Established Substrates Ral GTPases

The human genome contains six genes coding for proteins validated in vitro as specific activators of the small GTPases “Ras-related protein Ral-A” and “Ras-related protein Ral-B”, generically named Ral-guanine nucleotide exchange factors (RalGEF). Ral proteins are important contributors to Ras oncog...

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Pubblicato in:PLoS One
Autori principali: O. Santos, Adriana, Parrini, Maria Carla, Camonis, Jacques
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858283/
https://ncbi.nlm.nih.gov/pubmed/27149377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154840
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