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RalGPS2 Is Essential for Survival and Cell Cycle Progression of Lung Cancer Cells Independently of Its Established Substrates Ral GTPases

The human genome contains six genes coding for proteins validated in vitro as specific activators of the small GTPases “Ras-related protein Ral-A” and “Ras-related protein Ral-B”, generically named Ral-guanine nucleotide exchange factors (RalGEF). Ral proteins are important contributors to Ras oncog...

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Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: O. Santos, Adriana, Parrini, Maria Carla, Camonis, Jacques
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858283/
https://ncbi.nlm.nih.gov/pubmed/27149377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154840
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