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Structural study of the Cdc25 domain from Ral-specific guanine-nucleotide exchange factor RalGPS1a
The guanine-nucleotide exchange factor (GEF) RalGPS1a activates small GTPase Ral proteins such as RalA and RalB by stimulating the exchange of Ral bound GDP to GTP, thus regulating various downstream cellular processes. RalGPS1a is composed of an Nterminal Cdc25-like catalytic domain, followed by a...
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| Publié dans: | Protein Cell |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Higher Education Press
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4875206/ https://ncbi.nlm.nih.gov/pubmed/21494904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-011-1036-z |
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