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Structural study of the Cdc25 domain from Ral-specific guanine-nucleotide exchange factor RalGPS1a

The guanine-nucleotide exchange factor (GEF) RalGPS1a activates small GTPase Ral proteins such as RalA and RalB by stimulating the exchange of Ral bound GDP to GTP, thus regulating various downstream cellular processes. RalGPS1a is composed of an Nterminal Cdc25-like catalytic domain, followed by a...

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Detalhes bibliográficos
Publicado no:Protein Cell
Main Authors: Peng, Wei, Xu, Jiwei, Guan, Xiaotao, Sun, Yao, Zhang, Xuejun C., Li, Xuemei, Rao, Zihe
Formato: Artigo
Idioma:Inglês
Publicado em: Higher Education Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875206/
https://ncbi.nlm.nih.gov/pubmed/21494904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-011-1036-z
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