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A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange

Dbl-related oncoproteins are guanine nucleotide exchange factors (GEFs) specific for Rho guanosine triphosphatases (GTPases) and invariably possess tandem Dbl (DH) and pleckstrin homology (PH) domains. While it is known that the DH domain is the principal catalytic subunit, recent biochemical data i...

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Bibliografski detalji
Glavni autori: Rossman, Kent L., Worthylake, David K., Snyder, Jason T., Siderovski, David P., Campbell, Sharon L., Sondek, John
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2002
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC125919/
https://ncbi.nlm.nih.gov/pubmed/11889037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.6.1315
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