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A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange
Dbl-related oncoproteins are guanine nucleotide exchange factors (GEFs) specific for Rho guanosine triphosphatases (GTPases) and invariably possess tandem Dbl (DH) and pleckstrin homology (PH) domains. While it is known that the DH domain is the principal catalytic subunit, recent biochemical data i...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125919/ https://ncbi.nlm.nih.gov/pubmed/11889037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.6.1315 |
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