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Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease
The aberrant activity of Ras homologous (Rho) family small GTPases (20 human members) has been implicated in cancer and other human diseases. However, in contrast to the direct mutational activation of Ras found in cancer and developmental disorders, Rho GTPases are activated most commonly by indire...
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| Publié dans: | Oncogene |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4875565/ https://ncbi.nlm.nih.gov/pubmed/24037532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.362 |
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