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Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease

The aberrant activity of Ras homologous (Rho) family small GTPases (20 human members) has been implicated in cancer and other human diseases. However, in contrast to the direct mutational activation of Ras found in cancer and developmental disorders, Rho GTPases are activated most commonly by indire...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Cook, Danielle R., Rossman, Kent L., Der, Channing J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875565/
https://ncbi.nlm.nih.gov/pubmed/24037532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.362
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