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Leukemia-Associated Rho Guanine Nucleotide Exchange Factor Promotes Gαq-Coupled Activation of RhoA

Leukemia-associated Rho guanine-nucleotide exchange factor (LARG) belongs to the subfamily of Dbl homology RhoGEF proteins (including p115 RhoGEF and PDZ-RhoGEF) that possess amino-terminal regulator of G protein signaling (RGS) boxes also found within GTPase-accelerating proteins (GAPs) for heterot...

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Bibliographic Details
Main Authors: Booden, Michelle A., Siderovski, David P., Der, Channing J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC133844/
https://ncbi.nlm.nih.gov/pubmed/12024019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.12.4053-4061.2002
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