Contributions of the RhoA guanine nucleotide exchange factor Net1 to polyoma middle T antigen-mediated mammary gland tumorigenesis and metastasis

Abstract Background The RhoA activating protein Net1 contributes to breast cancer cell proliferation, motility, and invasion in vitro, yet little is known about its roles in mammary gland tumorigenesis and metastasis. Methods Net1 knockout (KO) mice were bred to mice with mammary gland specific expr...

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Detalles Bibliográficos

Autores principales:	Yan Zuo, Arzu Ulu, Jeffrey T. Chang, Jeffrey A. Frost
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2018-05-01
Colección:	Breast Cancer Research
Materias:	RhoA Net1 Polyoma middle T antigen Breast cancer Metastasis
Acceso en línea:	http://link.springer.com/article/10.1186/s13058-018-0966-2
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