Contributions of the RhoA guanine nucleotide exchange factor Net1 to polyoma middle T antigen-mediated mammary gland tumorigenesis and metastasis
Abstract Background The RhoA activating protein Net1 contributes to breast cancer cell proliferation, motility, and invasion in vitro, yet little is known about its roles in mammary gland tumorigenesis and metastasis. Methods Net1 knockout (KO) mice were bred to mice with mammary gland specific expr...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2018-05-01
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| Serie: | Breast Cancer Research |
| Soggetti: | |
| Accesso online: | http://link.springer.com/article/10.1186/s13058-018-0966-2 |
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