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Structural study of the Cdc25 domain from Ral-specific guanine-nucleotide exchange factor RalGPS1a

The guanine-nucleotide exchange factor (GEF) RalGPS1a activates small GTPase Ral proteins such as RalA and RalB by stimulating the exchange of Ral bound GDP to GTP, thus regulating various downstream cellular processes. RalGPS1a is composed of an Nterminal Cdc25-like catalytic domain, followed by a...

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Bibliografiske detaljer
Udgivet i:Protein Cell
Main Authors: Peng, Wei, Xu, Jiwei, Guan, Xiaotao, Sun, Yao, Zhang, Xuejun C., Li, Xuemei, Rao, Zihe
Format: Artigo
Sprog:Inglês
Udgivet: Higher Education Press 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875206/
https://ncbi.nlm.nih.gov/pubmed/21494904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-011-1036-z
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