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Structural study of the Cdc25 domain from Ral-specific guanine-nucleotide exchange factor RalGPS1a

The guanine-nucleotide exchange factor (GEF) RalGPS1a activates small GTPase Ral proteins such as RalA and RalB by stimulating the exchange of Ral bound GDP to GTP, thus regulating various downstream cellular processes. RalGPS1a is composed of an Nterminal Cdc25-like catalytic domain, followed by a...

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Dades bibliogràfiques
Publicat a:Protein Cell
Autors principals: Peng, Wei, Xu, Jiwei, Guan, Xiaotao, Sun, Yao, Zhang, Xuejun C., Li, Xuemei, Rao, Zihe
Format: Artigo
Idioma:Inglês
Publicat: Higher Education Press 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875206/
https://ncbi.nlm.nih.gov/pubmed/21494904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-011-1036-z
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