Structural study of the Cdc25 domain from Ral-specific guanine-nucleotide exchange factor RalGPS1a

The guanine-nucleotide exchange factor (GEF) RalGPS1a activates small GTPase Ral proteins such as RalA and RalB by stimulating the exchange of Ral bound GDP to GTP, thus regulating various downstream cellular processes. RalGPS1a is composed of an Nterminal Cdc25-like catalytic domain, followed by a...

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Publicado en:Protein Cell
Autores principales: Peng, Wei, Xu, Jiwei, Guan, Xiaotao, Sun, Yao, Zhang, Xuejun C., Li, Xuemei, Rao, Zihe
Formato: Artigo
Lenguaje:Inglês
Publicado: Higher Education Press 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875206/
https://ncbi.nlm.nih.gov/pubmed/21494904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-011-1036-z
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