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Inhibition of Ral GTPases Using a Stapled Peptide Approach
Aberrant Ras signaling drives numerous cancers, and drugs to inhibit this are urgently required. This compelling clinical need combined with recent innovations in drug discovery including the advent of biologic therapeutic agents, has propelled Ras back to the forefront of targeting efforts. Activat...
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| Опубликовано в: : | J Biol Chem |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5000079/ https://ncbi.nlm.nih.gov/pubmed/27334922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.720243 |
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