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Progress in the therapeutic inhibition of Cdc42 signalling
Cdc42 is a member of the Rho family of small GTPases and a key regulator of the actin cytoskeleton, controlling cell motility, polarity and cell cycle progression. It signals downstream of the master regulator Ras and is essential for cell transformation by this potent oncogene. Overexpression of Cd...
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| Udgivet i: | Biochem Soc Trans |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Portland Press Ltd.
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8286826/ https://ncbi.nlm.nih.gov/pubmed/34100887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20210112 |
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