Caricamento...

Replication past a trans-4-Hydroxynonenal Minor-Groove Adduct by the Sequential Action of Human DNA Polymerases ι and κ

The X-ray crystal structure of human DNA polymerase ι (Polι) has shown that it differs from all known Pols in its dependence upon Hoogsteen base pairing for synthesizing DNA. Hoogsteen base pairing provides an elegant mechanism for synthesizing DNA opposite minor-groove adducts that present a severe...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Wolfle, William T., Johnson, Robert E., Minko, Irina G., Lloyd, R. Stephen, Prakash, Satya, Prakash, Louise
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1317639/
https://ncbi.nlm.nih.gov/pubmed/16354708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.1.381-386.2006
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !