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Yeast DNA polymerase η makes functional contacts with the DNA minor groove only at the incoming nucleoside triphosphate

DNA polymerase η (Polη) functions in the proficient bypass of a variety of DNA lesions. Relative to the replicative polymerases, Polη has a greater tolerance for distorted DNA geometries and possesses a low fidelity. X-ray crystal structures and studies with nucleotide analogs have implicated intera...

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Detalhes bibliográficos
Main Authors: Washington, M. Todd, Wolfle, William T., Spratt, Thomas E., Prakash, Louise, Prakash, Satya
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC154307/
https://ncbi.nlm.nih.gov/pubmed/12692307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0837578100
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