Yeast DNA polymerase η makes functional contacts with the DNA minor groove only at the incoming nucleoside triphosphate

DNA polymerase η (Polη) functions in the proficient bypass of a variety of DNA lesions. Relative to the replicative polymerases, Polη has a greater tolerance for distorted DNA geometries and possesses a low fidelity. X-ray crystal structures and studies with nucleotide analogs have implicated intera...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Washington, M. Todd, Wolfle, William T., Spratt, Thomas E., Prakash, Louise, Prakash, Satya
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2003
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154307/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12692307/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0837578100
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