Efficient and Error-Free Replication Past a Minor-Groove DNA Adduct by the Sequential Action of Human DNA Polymerases ι and κ

DNA polymerase ι (Polι) is a member of the Y family of DNA polymerases, which promote replication through DNA lesions. The role of Polι in lesion bypass, however, has remained unclear. Polι is highly unusual in that it incorporates nucleotides opposite different template bases with very different ef...

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Autores principales: Washington, M. Todd, Minko, Irina G., Johnson, Robert E., Wolfle, William T., Harris, Thomas M., Lloyd, R. Stephen, Prakash, Satya, Prakash, Louise
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
DNA Dynamics and Chromosome Structure
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC480884/
https://ncbi.nlm.nih.gov/pubmed/15199127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.13.5687-5693.2004
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