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Replication past a trans-4-Hydroxynonenal Minor-Groove Adduct by the Sequential Action of Human DNA Polymerases ι and κ

The X-ray crystal structure of human DNA polymerase ι (Polι) has shown that it differs from all known Pols in its dependence upon Hoogsteen base pairing for synthesizing DNA. Hoogsteen base pairing provides an elegant mechanism for synthesizing DNA opposite minor-groove adducts that present a severe...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wolfle, William T., Johnson, Robert E., Minko, Irina G., Lloyd, R. Stephen, Prakash, Satya, Prakash, Louise
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1317639/
https://ncbi.nlm.nih.gov/pubmed/16354708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.1.381-386.2006
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