Upregulation of Protein Phosphatase 2Ac by Hepatitis C Virus Modulates NS3 Helicase Activity through Inhibition of Protein Arginine Methyltransferase 1

Hepatitis C virus (HCV) is a major cause of chronic liver disease, cirrhosis, and hepatocellular carcinoma worldwide. HCV has a positive-strand RNA genome of about 9.4 kb in size, which serves as a template for replication and for translation of a polyprotein of about 3,000 amino acids. The polyprot...

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Detalhes bibliográficos
Main Authors: Duong, Francois H. T., Christen, Verena, Berke, Jan Martin, Penna, Sabina Hernandez, Moradpour, Darius, Heim, Markus H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1315989/
https://ncbi.nlm.nih.gov/pubmed/16306605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.24.15342-15350.2005
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