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Structural biology and chemistry of protein arginine methyltransferases

Protein arginine methyltransferases (PRMTs), an emerging target class in drug discovery, can methylate histones and other substrates, and can be divided into three subgroups, based on the methylation pattern of the reaction product (monomethylation, symmetrical or asymmetrical dimethylation). Here,...

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Detalhes bibliográficos
Publicado no:Medchemcomm
Main Authors: Schapira, Matthieu, Ferreira de Freitas, Renato
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655611/
https://ncbi.nlm.nih.gov/pubmed/26693001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4md00269e
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