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Structural biology and chemistry of protein arginine methyltransferases

Protein arginine methyltransferases (PRMTs), an emerging target class in drug discovery, can methylate histones and other substrates, and can be divided into three subgroups, based on the methylation pattern of the reaction product (monomethylation, symmetrical or asymmetrical dimethylation). Here,...

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Bibliografische gegevens
Gepubliceerd in:Medchemcomm
Hoofdauteurs: Schapira, Matthieu, Ferreira de Freitas, Renato
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Royal Society of Chemistry 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655611/
https://ncbi.nlm.nih.gov/pubmed/26693001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4md00269e
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