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Structural biology and chemistry of protein arginine methyltransferases
Protein arginine methyltransferases (PRMTs), an emerging target class in drug discovery, can methylate histones and other substrates, and can be divided into three subgroups, based on the methylation pattern of the reaction product (monomethylation, symmetrical or asymmetrical dimethylation). Here,...
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Publicado no: | Medchemcomm |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Royal Society of Chemistry
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4655611/ https://ncbi.nlm.nih.gov/pubmed/26693001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4md00269e |
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