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The Arginine-1493 Residue in QRRGRTGR1493G Motif IV of the Hepatitis C Virus NS3 Helicase Domain Is Essential for NS3 Protein Methylation by the Protein Arginine Methyltransferase 1

The NS3 protein of hepatitis C virus (HCV) contains protease and RNA helicase activities, both of which are likely to be essential for HCV propagation. An arginine residue present in the arginine-glycine (RG)-rich region of many RNA-binding proteins is posttranslationally methylated by protein argin...

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Detalhes bibliográficos
Main Authors: Rho, Jaerang, Choi, Seeyoung, Seong, Young Rim, Choi, Joonho, Im, Dong-Soo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC115047/
https://ncbi.nlm.nih.gov/pubmed/11483748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.17.8031-8044.2001
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