Myosin phosphatase and RhoA-activated kinase modulate arginine methylation by the regulation of protein arginine methyltransferase 5 in hepatocellular carcinoma cells

Myosin phosphatase (MP) holoenzyme is a protein phosphatase-1 (PP1) type Ser/Thr specific enzyme that consists of a PP1 catalytic (PP1c) and a myosin phosphatase target subunit-1 (MYPT1). MYPT1 is an ubiquitously expressed isoform and it targets PP1c to its substrates. We identified the protein argi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sipos, Adrienn, Iván, Judit, Bécsi, Bálint, Darula, Zsuzsanna, Tamás, István, Horváth, Dániel, Medzihradszky, Katalin F., Erdődi, Ferenc, Lontay, Beáta
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225440/
https://ncbi.nlm.nih.gov/pubmed/28074910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40590
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