Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP
Dicer is a multi-domain RNase III-related endonuclease responsible for processing double-stranded RNA (dsRNA) to small interfering RNAs (siRNAs) during a process of RNA interference (RNAi). It also catalyses excision of the regulatory microRNAs from their precursors. In this work, we describe the pu...
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| Publicado no: | EMBO J |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC131079/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12411505/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf582 |
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