Caricamento...

Loss of spr-5 bypasses the requirement for the C.elegans presenilin sel-12 by derepressing hop-1

Presenilins are part of a protease complex that is responsible for the intramembraneous cleavage of the amyloid precursor protein involved in Alzheimer’s disease and of Notch receptors. In Caenorhabditis elegans, mutations in the presenilin sel-12 result in a highly penetrant egg-laying defect. spr-...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Eimer, S., Lakowski, B., Donhauser, R., Baumeister, R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2002
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC131058/
https://ncbi.nlm.nih.gov/pubmed/12411496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf561
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !