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SEL-8, a nuclear protein required for LIN-12 and GLP-1 signaling in Caenorhabditis elegans

LIN-12 and GLP-1 are members of the LIN-12/Notch family of receptors that mediate cell–cell interactions during development. The sel-8 gene had been identified previously in a screen for suppressors of a mutation that constitutively activates LIN-12. Here, we report that sel-8 is essential for lin-1...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Doyle, Timothy G., Wen, Chenhui, Greenwald, Iva
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC16638/
https://ncbi.nlm.nih.gov/pubmed/10884418
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