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SEL-8, a nuclear protein required for LIN-12 and GLP-1 signaling in Caenorhabditis elegans

LIN-12 and GLP-1 are members of the LIN-12/Notch family of receptors that mediate cell–cell interactions during development. The sel-8 gene had been identified previously in a screen for suppressors of a mutation that constitutively activates LIN-12. Here, we report that sel-8 is essential for lin-1...

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Detalles Bibliográficos
Main Authors: Doyle, Timothy G., Wen, Chenhui, Greenwald, Iva
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC16638/
https://ncbi.nlm.nih.gov/pubmed/10884418
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