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Suppressors of the egg-laying defective phenotype of sel-12 presenilin mutants implicate the CoREST corepressor complex in LIN-12/Notch signaling in C. elegans

Presenilin is an essential component of the LIN-12/Notch signaling pathway and also plays a critical role in the genesis of Alzheimer's disease. Previously, a screen for suppressors of the egg-laying defective phenotype caused by partial loss of presenilin activity in Caenorhabditis elegans ide...

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Bibliografiske detaljer
Main Authors: Jarriault, Sophie, Greenwald, Iva
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC187465/
https://ncbi.nlm.nih.gov/pubmed/12381669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1022402
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