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Endocrine self and gut non-self intersect in the pancreatic lymph nodes
The autoimmune cascade that culminates in diabetes initiates within pancreatic lymph nodes (PLNs). Here, we show that developmentally controlled lymphogenesis establishes a preferential trafficking route from the gut to the PLN, where T cells can be activated by antigens drained from the peritoneum...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1308925/ https://ncbi.nlm.nih.gov/pubmed/16317068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509006102 |
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