Endocrine self and gut non-self intersect in the pancreatic lymph nodes

The autoimmune cascade that culminates in diabetes initiates within pancreatic lymph nodes (PLNs). Here, we show that developmentally controlled lymphogenesis establishes a preferential trafficking route from the gut to the PLN, where T cells can be activated by antigens drained from the peritoneum...

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Hlavní autoři: Turley, Shannon J., Lee, Je-Wook, Dutton-Swain, Nick, Mathis, Diane, Benoist, Christophe
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2005
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1308925/
https://ncbi.nlm.nih.gov/pubmed/16317068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509006102
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