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Lymph node stroma broaden the peripheral tolerance paradigm
Research into how self-reactive T cells are tolerized in lymph nodes has focused largely on dendritic cells (DCs). We now know that lymph node stromal cells (LNSC) are important mediators of deletional tolerance to peripheral tissue-restricted antigens (PTAs). PTAs are constitutively expressed and p...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3163075/ https://ncbi.nlm.nih.gov/pubmed/21147035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2010.11.002 |
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