Entropy Calculation of HIV-1 Env gp120, its Receptor CD4, and their Complex: An Analysis of Configurational Entropy Changes upon Complexation

The HIV-1 gp120/CD4 interaction shows a large, unprecedented entropy/enthalpy compensation, with the capacity to fine-tune recognition over a broad range of affinity. The intermolecular interaction involves stable hydrophobic contacts with a unique protruding CD4-Phe(43) structure surrounded by an i...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Hsu, Shang-Te D., Peter, Christine, van Gunsteren, Wilfred F., Bonvin, Alexandre M. J. J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Biophysical Society 2005
Ämnen:
Biophysical Theory and Modeling
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304994/
https://ncbi.nlm.nih.gov/pubmed/15489307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.044933
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk