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A Functional Interaction between gp41 and gp120 Is Observed for Monomeric but Not Oligomeric, Uncleaved HIV-1 Env gp140

The envelope glycoprotein (Env) is the sole antigenic feature on the surface of HIV and the target for the humoral immune system. Soluble, uncleaved gp140 Env constructs truncated at the transmembrane domain are being investigated intensively as potential vaccine immunogens by many groups, and under...

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Autores principales: Guttman, Miklos, Lee, Kelly K.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807357/
https://ncbi.nlm.nih.gov/pubmed/23966389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01681-13
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