Apocalmodulin and Ca(2+)Calmodulin-Binding Sites on the Ca(V)1.2 Channel

The cardiac L-type voltage-dependent calcium channel is responsible for initiating excitation-contraction coupling. Three sequences (amino acids 1609–1628, 1627–1652, and 1665–1685, designated A, C, and IQ, respectively) of its α(1) subunit contribute to calmodulin (CaM) binding and Ca(2+)-dependent...

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Autors principals: Tang, Wei, Halling, D. Brent, Black, D. J., Pate, Patricia, Zhang, Jia-Zheng, Pedersen, Steen, Altschuld, Ruth A., Hamilton, Susan L.
Format: Artigo
Idioma:Inglês
Publicat: Biophysical Society 2003
Matèries:
Channels, Receptors, and Transporters
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303330/
https://ncbi.nlm.nih.gov/pubmed/12944271
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