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Conformational Polymorphism of the Amyloidogenic Peptide Homologous to Residues 113–127 of the Prion Protein

Conformational transitions are thought to be the prime mechanism of amyloid formation in prion diseases. The prion proteins are known to exhibit polymorphic behavior that explains their ability of “conformation switching” facilitated by structured “seeds” consisting of transformed proteins. Oligopep...

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Main Authors: Satheeshkumar, K. S., Jayakumar, R.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303103/
https://ncbi.nlm.nih.gov/pubmed/12829502
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