Amyloidogenic peptide homologous to fragment 129–148 of human myocilin

Myocilin is a protein with a molecular weight near 50 kDa. It is expressed in almost all organs and tissues.(1) We showed that the peptide DQL ETQ TRE LET AYS NLL RD corresponding to N-terminal Leucine zipper motif (LZM) of the protein is able to form amyloid-like fibrils. The possible role of this...

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Detalhes bibliográficos
Main Authors: Egorov, Vladimir V., Grudinina, Natalia A., Lebedev, Dmitry V., Shaldzhyan, Aram A., Slita, Alexander V., Sirotkin, Alexey K., Vasin, Andrey V., Shavlovsky, Michael M.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783111/
https://ncbi.nlm.nih.gov/pubmed/23764838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.24239
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