A conservative mutant of a proteolytic fragment produced during fibril formation enhances fibrillogenesis

The fibrillogenesis of a peptide corresponding to residues 35–51 of human α-lactalbumin ((1)GYDTQAIVENNESTEYG(17)) can be dramatically enhanced by the addition of a tetrapeptide TDYG homologous to its C-terminus (TEYG). Generation of spontaneous hydrolytic products similar to this peptide was demons...

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Detalhes bibliográficos
Publicado no:Prion
Main Authors: Egorov, Vladimir V, Lebedev, Dmitry V, Shaldzhyan, Aram A, Sirotkin, Alexey K, Gorshkov, Andrey N, Mirgorodskaya, Olga A, Grudinina, Natalia A, Vasin, Andrey V, Shavlovsky, Michael M
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601391/
https://ncbi.nlm.nih.gov/pubmed/25551549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19336896.2014.983745
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