Selectin-like kinetics and biomechanics promote rapid platelet adhesion in flow: the GPIb(alpha)-vWF tether bond.

The ability of platelets to tether to and translocate on injured vascular endothelium relies on the interaction between the platelet glycoprotein receptor Ib alpha (GPIb(alpha)) and the A1 domain of von Willebrand factor (vWF-A1). To date, limited information exists on the kinetics that govern plate...

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Hauptverfasser: Doggett, Teresa A, Girdhar, Gaurav, Lawshé, Avril, Schmidtke, David W, Laurenzi, Ian J, Diamond, Scott L, Diacovo, Thomas G
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2002
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302139/
https://ncbi.nlm.nih.gov/pubmed/12080112
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