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Significance of ligand tails for interaction with the minor groove of B-DNA.

Minor groove binding ligands are of great interest due to their extraordinary importance as transcription controlling drugs. We performed three molecular dynamics simulations of the unbound d(CGCGAATTCGCG)(2) dodecamer and its complexes with Hoechst33258 and Netropsin. The structural behavior of the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wellenzohn, B, Flader, W, Winger, R H, Hallbrucker, A, Mayer, E, Liedl, K R
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2001
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301637/
https://ncbi.nlm.nih.gov/pubmed/11509372
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