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A role for water molecules in DNA-ligand minor groove recognition
Targeting the minor groove of DNA through binding to a small molecule has long been considered an important molecular-recognition strategy in biology. A wide range of synthetic heterocyclic molecules bind non-covalently in the minor groove of the double helix and are also effective against a number...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2668807/ https://ncbi.nlm.nih.gov/pubmed/18798655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ar800016q |
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