טוען...
Small-molecule binding to the DNA minor groove is mediated by a conserved water cluster
High-resolution crystal structures of the DNA duplex sequence d(CGCGAATTCGCG)(2) complexed with three minor-groove ligands, are reported. A highly-conserved cluster, of eleven linked water molecules, has been found in the native and all three ligand-bound structures, positioned at the boundary of th...
שמור ב:
| Main Authors: | , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3580125/ https://ncbi.nlm.nih.gov/pubmed/23276263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja308952y |
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