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Hydration Changes Accompanying the Binding of Minor Groove Ligands with DNA

4′,6-Diamidino-2-phenylindole (DAPI), netropsin, and pentamidine are minor groove binders that have terminal − [Formula: see text] groups. The hydration changes that accompany their binding to the minor groove of the (AATT)(2) sequence have been studied using the osmotic stress technique with fluore...

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Autores principales: Degtyareva, Natalya N., Wallace, Bret D., Bryant, Andrea R., Loo, Kristine M., Petty, Jeffrey T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Biophysical Society 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779984/
https://ncbi.nlm.nih.gov/pubmed/17114230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.097451
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