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What drives the binding of minor groove-directed ligands to DNA hairpins?

Understanding the molecular basis of ligand–DNA-binding events, and its application to the rational design of novel drugs, requires knowledge of the structural features and forces that drive the corresponding recognition processes. Existing structural evidence on DNA complexation with classical mino...

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Detalhes bibliográficos
Main Authors: Lah, Jurij, Drobnak, Igor, Dolinar, Marko, Vesnaver, Gorazd
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2241884/
https://ncbi.nlm.nih.gov/pubmed/18086706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm1110
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