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Influence of a Hairpin Loop on the Thermodynamic Stability of a DNA Oligomer

DSC was used to evaluate the mechanism of the thermally induced unfolding of the single-stranded hairpin HP = 5′-CGGAATTCCGTCTCCGGAATTCCG-3′ and its core duplex D (5′-CGGAATTCCG-3′)(2). The DSC melting experiments performed at several salt concentrations were successfully described for HP and D in t...

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Detalhes bibliográficos
Main Authors: Lah, Jurij, Seručnik, Mojca, Vesnaver, Gorazd
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE-Hindawi Access to Research 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166569/
https://ncbi.nlm.nih.gov/pubmed/21904665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/513910
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