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Blockers of VacA provide insights into the structure of the pore.

The cytotoxic effects of the Helicobacter pylori toxin VacA, an important etiogenic factor in human gastric diseases, are due to its ability to form anion-selective pores in target cell membranes. We have studied the inhibition of channel activity by 5-nitro-2-(3-phenylpropylamino) benzoic acid (NPP...

詳細記述

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書誌詳細
主要な著者: Tombola, F, Del Giudice, G, Papini, E, Zoratti, M
フォーマット: Artigo
言語:Inglês
出版事項: 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1300984/
https://ncbi.nlm.nih.gov/pubmed/10920018
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