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How the loop and middle regions influence the properties of Helicobacter pylori VacA channels.

VacA is a pore-forming cytotoxin produced by Helicobacter pylori in several strain-specific isoforms, which have been classified in two main families, m1 and m2, according to the sequence of a variable "midregion." Both forms are associated with gastric pathologies and can induce vacuolati...

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Autors principals: Tombola, F, Pagliaccia, C, Campello, S, Telford, J L, Montecucco, C, Papini, E, Zoratti, M
Format: Artigo
Idioma:Inglês
Publicat: 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301780/
https://ncbi.nlm.nih.gov/pubmed/11720986
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