The Helicobacter pylori VacA toxin is a urea permease that promotes urea diffusion across epithelia

Urease and the cytotoxin VacA are two major virulence factors of the human pathogen Helicobacter pylori, which is responsible for severe gastroduodenal diseases. Diffusion of urea, the substrate of urease, into the stomach is critically required for the survival of infecting H. pylori. We now show t...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Tombola, Francesco, Morbiato, Laura, Del Giudice, Giuseppe, Rappuoli, Rino, Zoratti, Mario, Papini, Emanuele
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC200932/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11560962/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI13045
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